L’inhibition ciblée des kinases DAPK1/3 réduit la proportion des cellules HuRBas à prolifération lente et la réponse adaptative de l’ensemble des cellules malignes à un inhibiteur BRAF
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Targeted inhibition of the DAPKs (Death-associated protein kinase 1 and 3) reduces the proportion of slow-proliferating/senescent-like HuRLow cells and the adaptive response of the whole melanoma-cell population to BRAF inhibition.
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